General
Preferred name
UNC0064-12
Synonyms
UNC0064-12 hydrochloride (1430089-64-7(free base)) ()
2, 4-Pyrimidinediamine with linker ()
VEGFR-2-IN-5 ()
VEGFR-2-IN-5 (hydrochloride) ()
2,4-Pyrimidinediamine with linker ()
P&D ID
PD055917
CAS
2700435-52-3
1430089-64-7
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
4
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
364.21
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
5
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
3
cLogP
3.33
TPSA
116.57
Fraction CSP3
0.32
Chiral centers
0.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Angiogenesis
Tyrosine Kinase/Adaptors
Protein Tyrosine Kinase/RTK
Target
VEGFR2
VEGFR
Source data
