General
Preferred name
FRAXETIN
Synonyms
7,8-dihydroxy-6-methoxy coumarin ()
P&D ID
PD056320
CAS
574-84-5
Tags
natural product
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Fraxetin isolated from the bark of Fraxinus brngeana DC. It has protective against rotenone-induced cytotoxicity and apoptotic death. (BOC Sciences Bioactive Compounds)
Cell lines
2
Organisms
0
Compound Sets
6
AdooQ Bioactive Compound Library
A14554
BOC Sciences Bioactive Compounds
fraxetin-cas-574-84-5-464338
Cayman Chemical Bioactives
28011
MedChem Express Bioactive Compound Library
HY-N0580
Selleckchem Bioactive Compound Library
fraxetin
TargetMol Bioactive Compound Library
T2909
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
208.04
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.21
TPSA
79.9
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.54
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
MOA
human carbonic anhydrase 9?
Pathway
Apoptosis
Solubility
Soluble in DMSO (Slightly), Methanol (Slightly)
Target
Heme Oxygenase
Source data