General
Preferred name
Fagrocorat
Synonyms
DAGROCORAT ()
PF-00251802 ()
PF-00251802 (hydrochloride) ()
Dagrocorat (hydrochloride) ()
PF-802 ()
PF-0251802 ()
P&D ID
PD060765
CAS
1044535-52-5
1044535-61-6
Tags
available
drug candidate
Drug Status
investigational
experimental
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Dagrocorat (PF-00251802) is the active metabolite of prodrug . See the ligand page for the prodrug for further details of its development and potential clinical utility.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
DrugBank
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
494.22
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
3
cLogP
6.16
TPSA
62.22
Fraction CSP3
0.38
Chiral centers
3.0
Largest ring
6.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
Cytochrome P450
Glucocorticoid Receptor
Source data
