General
Preferred name
TEROXIRONE
Synonyms
TGIC ()
Triglycidyl isocyanurate ()
Triglycidyl Isocyanurate (Teroxirone) ()
Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC ()
GATGI ()
Henkel's compound ()
.alpha.-triglycidyl isocyanurate ()
NSC-296934 ()
Teroxirona ()
Alphatgi ()
P&D ID
PD062092
CAS
2451-62-9
28825-96-9
Tags
available
drug candidate
covalent binder
Drug Status
investigational
Max Phase
2.0
Drug indication
Antineoplastic
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
5
ChEMBL Drugs
CovalentInDB
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Properties
(calculated by RDKit )
Molecular Weight
297.1
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
-2.63
TPSA
103.59
Fraction CSP3
0.75
Chiral centers
3.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Target
MDM-2/p53
DNA/RNA Synthesis,p53
Source data
