General
Preferred name
pemafibrate
Synonyms
(R)-K-13675 ()
K-877 ()
Pemafibrato ()
K-13675, (r)- ()
P&D ID
PD064903
CAS
848259-27-8
Tags
available
drug
Approved by
PMDA
First approval
2017
Drug indication
Lipid metabolism disorder
Cardiovascular disease
Hyperlipidemia
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
490.21
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
13
Ring Count
4
Aromatic Ring Count
4
cLogP
5.55
TPSA
94.26
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
6.0
QED
0.24
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
DNA Damage/DNA Repair
Metabolism
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
hPPAR??
human PPAR??
PPAR??
PPAR
MOA
PPAR receptor agonist
Source data
