General
Preferred name
Glycohyocholic Acid
Synonyms
GHCA ()
Gly-¦Â-MCA ()
Gly MCA ()
Gly-??MCA ()
Gly-β-MCA ()
Glycine-β-muricholic Acid ()
Glycine-?-Muricholic Acid ()
Glycohyocholic Acid-d4 ()
P&D ID
PD076308
CAS
66225-78-3
32747-08-3
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Fluorescent retinoic acid analog; solvochromatic probe
(Tocris Bioactive Compound Library)
DESCRIPTION
Glycine-β-muricholic acid (GβMCA) is a potent, oral bioactive and intestine-selective antagonist of the farnesoid X receptor (FXR) that may be a candidate for the treatment of metabolic disorders.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
465.31
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
5
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
2.56
TPSA
127.09
Fraction CSP3
0.92
Chiral centers
11.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
LXR-like Receptors
MOA
Antagonist
Pathway
Autophagy
Metabolic Enzyme/Protease
Target
FXR
Endogenous Metabolite
Source data
