General
Preferred name
FMF-02-063-1
Synonyms
PI3Kδ/γ-IN-1 ()
PI3Kdelta/gamma-IN-1 ()
P&D ID
PD086798
CAS
1980884-01-2
Tags
available
probe
Probe info
Probe type
experimental probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
28
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA
Inhibitor
(Chemical Probes.org)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
6
Chemical Probes.org
CZ-OPENSCREEN Bioactive Library
Gray Laboratory Probes
High-quality chemical probes
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
7
Molecular Weight
508.19
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
3
cLogP
3.03
TPSA
118.97
Fraction CSP3
0.32
Chiral centers
0.0
Largest ring
7.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
PI3K-δ/γ Inhibitors
Target
PIK3CG
PIK3CD
PI3K
PIK3CD, PIK3CG
Pathway
PI3K/Akt/mTOR
Target class
Kinase, Kinase
Target subclass
PI3/PI4-kinase, PI3/PI4-kinase
Source data
