General
Preferred name
IM-156 FREE BASE
Synonyms
IM156 ()
HL156A ()
HL271 (acetate) ()
Lixumistat (acetate) ()
IM-156 (acetate) ()
HL271 ()
LIXUMISTAT ()
HL271 ACETATE ()
IM-156 ()
HL-156A ()
LIXUMISTAT ACETATE ()
P&D ID
PD134064
CAS
1422365-93-2
1422365-94-3
2043654-54-0
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
1.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
315.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
2.55
TPSA
84.23
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Epigenetics
Metabolic Enzyme/Protease
PI3K/Akt/mTOR
Target
oxidative phosphorylation (OXPHOS)
AMPK
Oxidative Phosphorylation
AMPK,Apoptosis related,OXPHOS
Source data
