Preferred name
OXOMEMAZINE
Synonyms
Oxomemazinum ()
RP-6847 ()
Oplex ()
6847-RP ()
Exe-top ()
6487-RP ()
Dysedon ()
Oxomemazina ()
RP 6847 ()
Trimeprazine 5,5-dioxide ()
Doxergan ()
Imakol ()
(?)-Oxomemazine ()
P&D ID
PD014405
CAS
3689-50-7
Tags
available
drug
Drug Status
withdrawn
approved
investigational
experimental
Max Phase
3.0
Structure
SMILES
CC(CN(C)C)CN1c2ccccc2S(=O)(=O)c2ccccc21
InChI
InChI=1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3
InChIkey
QTQPVLDZQVPLGV-UHFFFAOYSA-N
MOL
OXOMEMAZINE
RDKit 2D
23 25 0 0 0 0 0 0 0 0999 V2000
5.2500 -3.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.7500 -3.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.0000 -5.1962 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.7500 -6.4952 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
3.0000 -7.7942 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.2500 -6.4952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.0000 -2.5981 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5000 -2.5981 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 -1.2990 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5000 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 1.2990 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7500 1.2990 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5000 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7500 -1.2990 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5000 -2.5981 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0
-2.6491 -1.6339 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-2.6491 -3.5623 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
-0.7500 -3.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5000 -5.1962 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7500 -6.4952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 -6.4952 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5000 -5.1962 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 -3.8971 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1 2 1 0
2 3 1 0
3 4 1 0
4 5 1 0
4 6 1 0
2 7 1 0
7 8 1 0
8 9 1 0
9 10 2 0
10 11 1 0
11 12 2 0
12 13 1 0
13 14 2 0
14 15 1 0
15 16 2 0
15 17 2 0
15 18 1 0
18 19 2 0
19 20 1 0
20 21 2 0
21 22 1 0
22 23 2 0
23 8 1 0
14 9 1 0
23 18 1 0
M END
> <ID>
PD014405
> <Name>
OXOMEMAZINE
0
0
0
9
4
Cayman Chemical Bioactives
Mcule
MedChem Express Bioactive Compound Library
25
ChEMBL CHEMBL2104734
PubChem 19396
ACToR 3689-50-7
ChEBI 135408
ChemicalBook CB1236273
ChemSpider 18281
ClinicalTrials.gov OXOMEMAZINE
CompTox DTXSID5023405
DrugBank DB13820
DrugCentral 2025
HMDB HMDB0240230
IBM NIH 7F498F49627E654...
Mcule MCULE-8157601465
Nikkaji J8.210D
PubChem TPS 15421542
Reactome 18281
SureChEMBL SCHEMBL423634
(calculated by RDKit )
Molecular Weight
330.14
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
3.17
TPSA
40.62
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.86
0
No structural alerts detected
(extracted from source data)
ATC
R06AD08
Pathway
GPCR/G protein
Immunology/Inflammation
Neuronal Signaling
Target
Histamine Receptor
mGluR
